Mycobacterium tuberculosis complex bacteremia among HIV and non-HIV patients in a Mexican tertiary care center

ABSTRACT Objectives: To determine the factors associated with Mycobacterium tuberculosis complex-positive blood culture. Methods: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015. Results: We reviewed medical records of 533 patients with culture-proven tuberculosis, of whom 27.2% (145/533) had blood culture available. Patients with mycobacteremia presented more frequently with abdominal tuberculosis, body mass index <18 kg/m2, and had lower hemoglobin and albumin levels. No differences were observed regarding HIV status. Conclusions: Few studies have reported on the characteristics associated with Mycobacterium tuberculosis complex bacteremia, especially among Human Immunodeficiency Virus-negative patients. Out of 145 tuberculosis-infected patients with blood culture results available, 21 turned out positive. Anemia, hypoalbuminemia, and a body mass index < 18 kg/m2 were associated with mycobacteremia.

Isolation of mycobacterium avium complex and M Simiae from blood of AIDS patients from Sevagram, Maharashtra.

Background and Methodolgoy: Mycobacterium avium complex (MAC) has not been reported as an opportunistic pathogen among patients with AIDS in the Indian subcontinent. Blood samples were cultured for mycobacteria using BACTEC 460TB system from 71 HIV seropositive and 33 seronegative patients, tested at Mahatma Gandhi Institute of Medical Sciences, Sevagam between August 2001 and December 2002. Results: MAC and M. simiae were isolated from three patients each. All the six patients with mycobacteremia were AIDS cases. Clinically, none of them was diagnosed as a case of mycobacteremia. However, laboratory results confirmed the dissemination of MAC and M. simiae among these patients. Conclusion: These results confirm that disseminated MAC and M. simiae disease exist among AIDS patients in India also.